Global Intercellular Adhesion Molecule-1 (ICAM-1) Market
Strategic Market Analysis & Forecast (2026–2036)
Market Overview
Intercellular Adhesion Molecule-1 (ICAM-1) is a transmembrane glycoprotein involved in leukocyte adhesion, endothelial signaling, and inflammatory responses. ICAM-1 is a validated therapeutic and diagnostic target across inflammatory, autoimmune, dermatological, gastrointestinal, and urogenital disorders, and is increasingly explored in RNA-based, small-molecule, and biologic therapies.
The global ICAM-1 market was valued at USD XX million in 2020 and is projected to reach USD XX million by 2036, expanding at a CAGR of XX% during 2026–2036. Market growth is driven by rising incidence of chronic inflammatory diseases, increased biomarker-driven drug development, and advances in targeted and gene-silencing therapies.
Segments Analysis
By Product Type
-
DNP-003
Topical and localized ICAM-1 modulation therapies -
CMS-024
Systemic anti-inflammatory formulations -
MS-553
Targeted ICAM-1 pathway inhibitors -
Other ICAM-1 Targeting Therapies
Includes RNA-based drugs, monoclonal antibodies, and novel small molecules
By Therapeutic Modality (New Segmentation)
-
Small-Molecule Inhibitors
-
RNA Interference (RNAi) Therapies
-
Biologics & Antibody-Based Therapies
-
Combination & Adjunct Therapies
By Application
-
Dermatology
Psoriasis, atopic dermatitis, inflammatory skin disorders -
Genito-Urinary System & Sex Hormone Disorders
Inflammatory urogenital conditions -
Crohn’s Disease
High unmet need segment with strong pipeline activity -
Other Indications
Includes autoimmune, cardiovascular, and infectious diseases
By Treatment Setting (New Segmentation)
-
Hospitals
-
Specialty Clinics
-
Research & Academic Centers
Key Market Players
Major Manufacturers
-
Atlantic Healthcare Plc
-
China Medical System Holdings Ltd
-
RXi Pharmaceuticals Corp
Additional & Emerging Players (Added)
-
Pfizer
-
Novartis
-
Roche
-
AbbVie
-
Amgen
Regional Analysis
North America
-
Largest market share
-
Strong clinical trial activity and biologics adoption
-
Advanced regulatory and reimbursement frameworks
Europe
-
Mature market with strong inflammatory disease research
-
Growing adoption of targeted therapies
Asia-Pacific
-
Fastest-growing regional market
-
Increasing inflammatory disease prevalence
-
Expansion of pharmaceutical R&D in China, India, and Japan
Central & South America
-
Gradual market expansion
-
Increasing access to specialty therapeutics
Middle East & Africa
-
Emerging market
-
Growth driven by tertiary care centers and imports
Porter’s Five Forces Analysis
| Force | Impact |
|---|---|
| Threat of New Entrants | Low–Medium (high R&D and regulatory barriers) |
| Supplier Power | Medium (complex biologic inputs) |
| Buyer Power | High (hospital and payer control) |
| Threat of Substitutes | Medium (alternative inflammatory targets) |
| Competitive Rivalry | Medium–High (innovation-driven competition) |
SWOT Analysis
Strengths
-
Strong biological relevance of ICAM-1
-
Expanding therapeutic applications
-
Growing interest in precision medicine
Weaknesses
-
Limited approved ICAM-1-specific therapies
-
High development cost and long timelines
Opportunities
-
RNA-based and targeted biologic therapies
-
Expansion into autoimmune and gastrointestinal diseases
-
Biomarker-driven patient stratification
Threats
-
Competition from alternative inflammatory pathways
-
Regulatory complexity
-
Pricing and reimbursement pressures
Trend Analysis
-
Shift toward targeted and gene-silencing therapies
-
Increasing use of ICAM-1 as a biomarker
-
Growth in RNA-based inflammatory treatments
-
Expansion of precision immunology pipelines
-
Increased collaboration between biotech and pharma
Key Market Drivers
-
Rising prevalence of chronic inflammatory and autoimmune diseases
-
Advances in molecular biology and RNA therapeutics
-
Growing demand for targeted and steroid-sparing treatments
Challenges & Restraints
-
High R&D and clinical trial costs
-
Small and specialized patient populations
-
Limited long-term safety data for novel modalities
Value Chain Analysis
-
Target Identification & Preclinical Research
-
Drug Discovery & Molecular Engineering
-
Clinical Development (Phase I–III)
-
Regulatory Approval
-
Manufacturing & Quality Control
-
Distribution & Specialty Pharmacies
-
Hospitals, Clinics & Patients
Quick Strategic Recommendations for Stakeholders
-
Pharma & Biotech Companies: Focus on RNAi and biologic ICAM-1 modulators
-
Healthcare Providers: Integrate biomarker-driven treatment pathways
-
Investors: Target companies with late-stage ICAM-1 pipelines
-
Distributors: Build specialty distribution capabilities
-
Policy Makers: Support orphan and targeted inflammatory disease programs
Conclusion
The Intercellular Adhesion Molecule-1 (ICAM-1) market represents a high-potential, innovation-driven therapeutic segment within inflammatory and autoimmune disease management. As treatment paradigms shift toward precision immunology and targeted intervention, ICAM-1-focused therapies are expected to gain increasing clinical and commercial relevance.
Table of Contents
Global Intercellular Adhesion Molecule 1 Market Research Report 2026
1 Industry Overview of Intercellular Adhesion Molecule 1
1.1 Definition and Specifications of Intercellular Adhesion Molecule 1
1.1.1 Definition of Intercellular Adhesion Molecule 1
1.1.2 Specifications of Intercellular Adhesion Molecule 1
1.2 Classification of Intercellular Adhesion Molecule 1
1.2.1 DNP-003
1.2.2 CMS-024
1.2.3 MS-553
1.2.4 Others
1.3 Applications of Intercellular Adhesion Molecule 1
1.3.1 Dermatology
1.3.2 Genito Urinary System and Sex Hormones
1.3.3 Crohn's Disease
1.3.4 Others
1.4 Market Segment by Regions
1.4.1 North America
1.4.2 Europe
1.4.3 China
1.4.4 Japan
1.4.5 Southeast Asia
1.4.6 India
2 Manufacturing Cost Structure Analysis of Intercellular Adhesion Molecule 1
2.1 Raw Material and Suppliers
2.2 Manufacturing Cost Structure Analysis of Intercellular Adhesion Molecule 1
2.3 Manufacturing Process Analysis of Intercellular Adhesion Molecule 1
2.4 Industry Chain Structure of Intercellular Adhesion Molecule 1
3 Technical Data and Manufacturing Plants Analysis of Intercellular Adhesion Molecule 1
3.1 Capacity and Commercial Production Date of Global Intercellular Adhesion Molecule 1 Major Manufacturers
3.2 Manufacturing Plants Distribution of Global Intercellular Adhesion Molecule 1 Major Manufacturers
3.3 R&D Status and Technology Source of Global Intercellular Adhesion Molecule 1 Major Manufacturers
3.4 Raw Materials Sources Analysis of Global Intercellular Adhesion Molecule 1 Major Manufacturers
4 Global Intercellular Adhesion Molecule 1 Overall Market Overview
4.1 E Overall Market Analysis
4.2 Capacity Analysis
4.2.1 E Global Intercellular Adhesion Molecule 1 Capacity and Growth Rate Analysis
4.2.2 Intercellular Adhesion Molecule 1 Capacity Analysis (Company Segment)
4.3 Sales Analysis
4.3.1 E Global Intercellular Adhesion Molecule 1 Sales and Growth Rate Analysis
4.3.2 Intercellular Adhesion Molecule 1 Sales Analysis (Company Segment)
4.4 Sales Price Analysis
4.4.1 E Global Intercellular Adhesion Molecule 1 Sales Price
4.4.2 Intercellular Adhesion Molecule 1 Sales Price Analysis (Company Segment)
5 Intercellular Adhesion Molecule 1 Regional Market Analysis
5.1 North America Intercellular Adhesion Molecule 1 Market Analysis
5.1.1 North America Intercellular Adhesion Molecule 1 Market Overview
5.1.2 North America E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.1.3 North America E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.1.4 North America Intercellular Adhesion Molecule 1 Market Share Analysis
5.2 Europe Intercellular Adhesion Molecule 1 Market Analysis
5.2.1 Europe Intercellular Adhesion Molecule 1 Market Overview
5.2.2 Europe E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.2.3 Europe E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.2.4 Europe Intercellular Adhesion Molecule 1 Market Share Analysis
5.3 China Intercellular Adhesion Molecule 1 Market Analysis
5.3.1 China Intercellular Adhesion Molecule 1 Market Overview
5.3.2 China E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.3.3 China E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.3.4 China Intercellular Adhesion Molecule 1 Market Share Analysis
5.4 Japan Intercellular Adhesion Molecule 1 Market Analysis
5.4.1 Japan Intercellular Adhesion Molecule 1 Market Overview
5.4.2 Japan E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.4.3 Japan E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.4.4 Japan Intercellular Adhesion Molecule 1 Market Share Analysis
5.5 Southeast Asia Intercellular Adhesion Molecule 1 Market Analysis
5.5.1 Southeast Asia Intercellular Adhesion Molecule 1 Market Overview
5.5.2 Southeast Asia E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.5.3 Southeast Asia E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.5.4 Southeast Asia Intercellular Adhesion Molecule 1 Market Share Analysis
5.6 India Intercellular Adhesion Molecule 1 Market Analysis
5.6.1 India Intercellular Adhesion Molecule 1 Market Overview
5.6.2 India E Intercellular Adhesion Molecule 1 Local Supply, Import, Export, Local Consumption Analysis
5.6.3 India E Intercellular Adhesion Molecule 1 Sales Price Analysis
5.6.4 India Intercellular Adhesion Molecule 1 Market Share Analysis
6 Global E Intercellular Adhesion Molecule 1 Segment Market Analysis (by Type)
6.1 Global E Intercellular Adhesion Molecule 1 Sales by Type
6.2 Different Types of Intercellular Adhesion Molecule 1 Product Interview Price Analysis
6.3 Different Types of Intercellular Adhesion Molecule 1 Product Driving Factors Analysis
6.3.1 DNP-003 Growth Driving Factor Analysis
6.3.2 CMS-024 Growth Driving Factor Analysis
6.3.3 MS-553 Growth Driving Factor Analysis
6.3.4 Others Growth Driving Factor Analysis
7 Global E Intercellular Adhesion Molecule 1 Segment Market Analysis (by Application)
7.1 Global E Intercellular Adhesion Molecule 1 Consumption by Application
7.2 Different Application of Intercellular Adhesion Molecule 1 Product Interview Price Analysis
7.3 Different Application of Intercellular Adhesion Molecule 1 Product Driving Factors Analysis
7.3.1 Dermatology of Intercellular Adhesion Molecule 1 Growth Driving Factor Analysis
7.3.2 Genito Urinary System and Sex Hormones of Intercellular Adhesion Molecule 1 Growth Driving Factor Analysis
7.3.3 Crohn's Disease of Intercellular Adhesion Molecule 1 Growth Driving Factor Analysis
7.3.4 Others of Intercellular Adhesion Molecule 1 Growth Driving Factor Analysis
8 Major Manufacturers Analysis of Intercellular Adhesion Molecule 1
8.1 Atlantic Healthcare Plc
8.1.1 Company Profile
8.1.2 Product Picture and Specifications
8.1.2.1 Product A
8.1.2.2 Product B
8.1.3 Atlantic Healthcare Plc Intercellular Adhesion Molecule 1 Sales, Ex-factory Price, Revenue, Gross Margin Analysis
8.1.4 Atlantic Healthcare Plc Intercellular Adhesion Molecule 1 Business Region Distribution Analysis
8.2 China Medical System Holdings Ltd
8.2.1 Company Profile
8.2.2 Product Picture and Specifications
8.2.2.1 Product A
8.2.2.2 Product B
8.2.3 China Medical System Holdings Ltd Intercellular Adhesion Molecule 1 Sales, Ex-factory Price, Revenue, Gross Margin Analysis
8.2.4 China Medical System Holdings Ltd Intercellular Adhesion Molecule 1 Business Region Distribution Analysis
8.3 RXi Pharmaceuticals Corp
8.3.1 Company Profile
8.3.2 Product Picture and Specifications
8.3.2.1 Product A
8.3.2.2 Product B
8.3.3 RXi Pharmaceuticals Corp Intercellular Adhesion Molecule 1 Sales, Ex-factory Price, Revenue, Gross Margin Analysis
8.3.4 RXi Pharmaceuticals Corp Intercellular Adhesion Molecule 1 Business Region Distribution Analysis
9 Development Trend of Analysis of Intercellular Adhesion Molecule 1 Market
9.1 Global Intercellular Adhesion Molecule 1 Market Trend Analysis
9.1.1 Global Intercellular Adhesion Molecule 1 Market Size (Volume and Value) Forecast
9.1.2 Global Intercellular Adhesion Molecule 1 Sales Price Forecast
9.2 Intercellular Adhesion Molecule 1 Regional Market Trend
9.2.1 North America Intercellular Adhesion Molecule 1 Consumption Forecast
9.2.2 Europe Intercellular Adhesion Molecule 1 Consumption Forecast
9.2.3 China Intercellular Adhesion Molecule 1 Consumption Forecast
9.2.4 Japan Intercellular Adhesion Molecule 1 Consumption Forecast
9.2.5 Southeast Asia Intercellular Adhesion Molecule 1 Consumption Forecast
9.2.6 India Intercellular Adhesion Molecule 1 Consumption Forecast
9.3 Intercellular Adhesion Molecule 1 Market Trend (Product Type)
9.4 Intercellular Adhesion Molecule 1 Market Trend (Application)
10 Intercellular Adhesion Molecule 1 Marketing Type Analysis
10.1 Intercellular Adhesion Molecule 1 Regional Marketing Type Analysis
10.2 Intercellular Adhesion Molecule 1 International Trade Type Analysis
10.3 Traders or Distributors with Contact Information of Intercellular Adhesion Molecule 1 by Region
10.4 Intercellular Adhesion Molecule 1 Supply Chain Analysis
11 Consumers Analysis of Intercellular Adhesion Molecule 1
11.1 Consumer 1 Analysis
11.2 Consumer 2 Analysis
11.3 Consumer 3 Analysis
11.4 Consumer 4 Analysis
12 Conclusion of the Global Intercellular Adhesion Molecule 1 Market Professional Survey Report
Methodology
Analyst Introduction
Data Source
List of Tables and Figures
Figure Picture of Intercellular Adhesion Molecule 1
Table Product Specifications of Intercellular Adhesion Molecule 1
Table Classification of Intercellular Adhesion Molecule 1
Figure Global Production Market Share of Intercellular Adhesion Molecule 1 by Type in
Figure DNP-003 Picture
Table Major Manufacturers of DNP-003
Figure CMS-024 Picture
Table Major Manufacturers of CMS-024
Figure MS-553 Picture
Table Major Manufacturers of MS-553
Figure Others Picture
Table Major Manufacturers of Others
Table Applications of Intercellular Adhesion Molecule 1
Figure Global Consumption Volume Market Share of Intercellular Adhesion Molecule 1 by Application in
Figure Dermatology Examples
Table Major Consumers in Dermatology
Figure Genito Urinary System and Sex Hormones Examples
Table Major Consumers in Genito Urinary System and Sex Hormones
Figure Crohn's Disease Examples
Table Major Consumers in Crohn's Disease
Figure Others Examples
Table Major Consumers in Others
Figure Market Share of Intercellular Adhesion Molecule 1 by Regions
Figure North America Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Figure Europe Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Figure China Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Figure Japan Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Figure Southeast Asia Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Figure India Intercellular Adhesion Molecule 1 Market Size (Million USD) (2013-2025)
Table Intercellular Adhesion Molecule 1 Raw Material and Suppliers
Table Manufacturing Cost Structure Analysis of Intercellular Adhesion Molecule 1 in
Figure Manufacturing Process Analysis of Intercellular Adhesion Molecule 1
Figure Industry Chain Structure of Intercellular Adhesion Molecule 1
Table Capacity and Commercial Production Date of Global Intercellular Adhesion Molecule 1 Major Manufacturers
Table Manufacturing Plants Distribution of Global Intercellular Adhesion Molecule 1 Major Manufacturers
Table R&D Status and Technology Source of Global Intercellular Adhesion Molecule 1 Major Manufacturers
Table Raw Materials Sources Analysis of Global Intercellular Adhesion Molecule 1 Major Manufacturers
Table Global Capacity, Sales , Price, Cost, Sales Revenue (M USD) and Gross Margin of Intercellular Adhesion Molecule 1 E
Figure Global E Intercellular Adhesion Molecule 1 Market Size (Volume) and Growth Rate
Figure Global E Intercellular Adhesion Molecule 1 Market Size (Value) and Growth Rate
Table E Global Intercellular Adhesion Molecule 1 Capacity and Growth Rate
Table Global Intercellular Adhesion Molecule 1 Capacity (K Pcs) List (Company Segment)
Table E Global Intercellular Adhesion Molecule 1 Sales (K Pcs) and Growth Rate
Table Global Intercellular Adhesion Molecule 1 Sales (K Pcs) List (Company Segment)
Table E Global Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Table Global Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs) List (Company Segment)
Figure North America Capacity Overview
Table North America Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure North America E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure North America Intercellular Adhesion Molecule 1 Sales Market Share
Figure Europe Capacity Overview
Table Europe Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure Europe E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure Europe Intercellular Adhesion Molecule 1 Sales Market Share
Figure China Capacity Overview
Table China Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure China E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure China Intercellular Adhesion Molecule 1 Sales Market Share
Figure Japan Capacity Overview
Table Japan Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure Japan E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure Japan Intercellular Adhesion Molecule 1 Sales Market Share
Figure Southeast Asia Capacity Overview
Table Southeast Asia Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure Southeast Asia E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure Southeast Asia Intercellular Adhesion Molecule 1 Sales Market Share
Figure India Capacity Overview
Table India Supply, Import, Export and Consumption (K Pcs) of Intercellular Adhesion Molecule 1 E
Figure India E Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs)
Figure India Intercellular Adhesion Molecule 1 Sales Market Share
Table Global E Intercellular Adhesion Molecule 1 Sales (K Pcs) by Type
Table Different Types Intercellular Adhesion Molecule 1 Product Interview Price
Table Global E Intercellular Adhesion Molecule 1 Sales (K Pcs) by Application
Table Different Application Intercellular Adhesion Molecule 1 Product Interview Price
Table Atlantic Healthcare Plc Information List
Table Product Overview
Table Atlantic Healthcare Plc Intercellular Adhesion Molecule 1 Revenue (Million USD), Sales (K Pcs), Ex-factory Price (USD/Pcs)
Figure Atlantic Healthcare Plc Intercellular Adhesion Molecule 1 Business Region Distribution
Table China Medical System Holdings Ltd Information List
Table Product Overview
Table China Medical System Holdings Ltd Intercellular Adhesion Molecule 1 Revenue (Million USD), Sales (K Pcs), Ex-factory Price (USD/Pcs)
Figure China Medical System Holdings Ltd Intercellular Adhesion Molecule 1 Business Region Distribution
Table RXi Pharmaceuticals Corp Information List
Table Product Overview
Table RXi Pharmaceuticals Corp Intercellular Adhesion Molecule 1 Revenue (Million USD), Sales (K Pcs), Ex-factory Price (USD/Pcs)
Figure RXi Pharmaceuticals Corp Intercellular Adhesion Molecule 1 Business Region Distribution
Figure Global Intercellular Adhesion Molecule 1 Market Size (K Pcs) and Growth Rate Forecast
Figure Global Intercellular Adhesion Molecule 1 Market Size (Million USD) and Growth Rate Forecast
Figure Global Intercellular Adhesion Molecule 1 Sales Price (USD/Pcs) Forecast
Figure North America Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Figure China Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Figure Europe Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Figure Southeast Asia Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Figure Japan Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Figure India Intercellular Adhesion Molecule 1 Consumption Volume (K Pcs) and Growth Rate Forecast
Table Global Sales Volume (K Pcs) of Intercellular Adhesion Molecule 1 by Type
Table Global Consumption Volume (K Pcs) of Intercellular Adhesion Molecule 1 by Application
Table Traders or Distributors with Contact Information of Intercellular Adhesion Molecule 1 by Region
Segments Analysis
By Product Type
-
DNP-003
Topical and localized ICAM-1 modulation therapies -
CMS-024
Systemic anti-inflammatory formulations -
MS-553
Targeted ICAM-1 pathway inhibitors -
Other ICAM-1 Targeting Therapies
Includes RNA-based drugs, monoclonal antibodies, and novel small molecules
By Therapeutic Modality (New Segmentation)
-
Small-Molecule Inhibitors
-
RNA Interference (RNAi) Therapies
-
Biologics & Antibody-Based Therapies
-
Combination & Adjunct Therapies
By Application
-
Dermatology
Psoriasis, atopic dermatitis, inflammatory skin disorders -
Genito-Urinary System & Sex Hormone Disorders
Inflammatory urogenital conditions -
Crohn’s Disease
High unmet need segment with strong pipeline activity -
Other Indications
Includes autoimmune, cardiovascular, and infectious diseases
By Treatment Setting (New Segmentation)
-
Hospitals
-
Specialty Clinics
-
Research & Academic Centers
Key Market Players
Major Manufacturers
-
Atlantic Healthcare Plc
-
China Medical System Holdings Ltd
-
RXi Pharmaceuticals Corp
Additional & Emerging Players (Added)
-
Pfizer
-
Novartis
-
Roche
-
AbbVie
-
Amgen
