Global Glutamate Carboxypeptidase 2 Market Research Report 2026

Global Glutamate Carboxypeptidase 2 Market Research Report 2026

Pages: 210

Format: PDF

Date: 01-2026

This strategic report offers a comprehensive evaluation of the Global Glutamate Carboxypeptidase 2 (GCPII) Market, focusing on its dual significance as Prostate-Specific Membrane Antigen (PSMA) in oncology and NAALADase in neurology.


Global Glutamate Carboxypeptidase 2 Market: Strategic Analysis & Forecast (2026–2036)

1. Market Overview

The Glutamate Carboxypeptidase 2 (GCPII) market is undergoing a revolutionary shift, primarily driven by the "Theranostics" paradigm—combining targeted diagnostics with precision therapeutics. While initially recognized for its role in the central nervous system, GCPII’s overexpression in prostate cancer has made it one of the most valuable targets in nuclear medicine and oncology.

  • Market Valuation (2025): Estimated at USD 1.8 Billion.

  • Projected Valuation (2036): Expected to reach USD 5.2 Billion.

  • CAGR (2026–2036): Projected at 10.2%.

2. Key Players

Beyond the initial list of biotech firms, the market is now dominated by major pharmaceutical giants and radiopharmaceutical specialists:

  • Novartis AG (Switzerland) – Leader in PSMA-targeted radioligand therapy.

  • Lantheus Holdings, Inc. (USA) – Specialized in PSMA-PET imaging agents.

  • Telix Pharmaceuticals (Australia) – Focused on molecularly targeted radiation.

  • Bayer AG (Germany) – Developing alpha-emitting GCPII conjugates.

  • Eli Lilly (Point Biopharma) (USA) – Expanding into next-gen radioligands.

  • Amgen Inc. (USA) – Researching BiTE (Bispecific T-cell Engager) molecules targeting GCPII.

  • Curium (France) – Global leader in diagnostic isotope manufacturing.

  • Blue Earth Diagnostics (UK) – Specialized in molecular imaging for prostate cancer.

  • Avalo Therapeutics (formerly Cerecor) (USA).

  • Inovio Pharmaceuticals (USA).

3. Comprehensive Market Segmentation

By Product/Molecule Type

  • Radioligand Therapies: High-growth segment (e.g., Lu-177 labeled molecules).

  • Monoclonal Antibodies: Used for both delivery of toxins and immune activation.

  • Small Molecule Inhibitors: Primarily focused on neurological applications and PET imaging.

  • Bispecific Antibodies: Engineering immune cells to target GCPII-expressing tumors.

By Application

  • Oncology (Prostate Cancer): The largest segment, covering biochemical recurrence imaging and therapy for mCRPC (metastatic castration-resistant prostate cancer).

  • Neurology (CNS Disorders): Researching GCPII inhibition to treat neuropathic pain, Schizophrenia, and ALS by regulating synaptic glutamate.

  • Other Cancers: Emerging research into GCPII expression in the neovasculature of solid tumors (e.g., kidney and bladder cancers).

By End-User

  • Specialty Hospitals & Oncology Centers: Primary hubs for therapeutic administration.

  • Diagnostic Imaging Centers: Utilizing PSMA-PET scans for early detection.

  • Academic & Research Institutes: Driving the pipeline for CNS-related applications.

4. Regional Analysis

  • North America: Occupies the largest revenue share (approx. 45%). The rapid adoption of PSMA-PET imaging and FDA approvals for radioligand therapies drive this market.

  • Europe: A stronghold for radiopharmaceutical innovation, particularly in Germany and Switzerland, where early-access programs for targeted alpha therapy are prominent.

  • Asia-Pacific: The fastest-growing region. Increasing healthcare expenditure in China and India, combined with a rising incidence of prostate cancer, is driving localized manufacturing of GCPII-targeted agents.

  • LAMEA: Emerging infrastructure for nuclear medicine in Brazil and the GCC countries is creating new market entry points.

5. Porter’s Five Forces Analysis

  1. Bargaining Power of Suppliers (High): Suppliers of medical isotopes (Lutetium-177, Actinium-225) hold significant power due to limited global nuclear reactor capacity.

  2. Bargaining Power of Buyers (Moderate): Large oncology networks have some leverage, but the life-saving nature of these targeted therapies limits price sensitivity.

  3. Threat of New Entrants (Low): Massive capital requirements for specialized radiopharmaceutical labs and stringent nuclear regulatory hurdles act as formidable barriers.

  4. Threat of Substitutes (Moderate): Alternative targets like GRPR (Gastrin-Releasing Peptide Receptor) are in development, but GCPII remains the gold standard.

  5. Competitive Rivalry (High): Intense R&D race between Novartis, Bayer, and Telix to capture the first-line treatment market.

6. SWOT Analysis

  • Strengths: High specificity for prostate cancer cells; dual utility (imaging + therapy); well-validated clinical targets.

  • Weaknesses: High production costs; short half-life of radiopharmaceuticals requiring complex logistics.

  • Opportunities: Expansion into earlier stages of prostate cancer; therapeutic potential in chronic neuropathic pain.

  • Threats: Supply chain disruptions of raw isotopes; potential long-term toxicity concerns (e.g., salivary gland uptake).

7. Trend Analysis

  • Targeted Alpha Therapy (TAT): A shift from beta-emitters to alpha-emitters (like Actinium-225) to deliver higher energy to cancer cells with less collateral damage.

  • Artificial Intelligence in Imaging: AI algorithms are being used to quantify GCPII/PSMA expression levels on PET scans to predict patient response to therapy.

  • Precision Neurology: Growing interest in using GCPII inhibitors as "neuro-protectants" to prevent glutamate excitotoxicity in stroke and trauma.

8. Drivers & Challenges

  • Driver: The global aging male population and the increasing prevalence of prostate cancer.

  • Driver: The shift from "one-size-fits-all" chemotherapy to personalized molecular medicine.

  • Challenge: The "Just-in-Time" logistics required for radiopharmaceuticals—drugs must be manufactured and delivered within hours of patient administration.

  • Challenge: Limited global capacity for waste disposal of radioactive medical byproducts.

9. Value Chain Analysis

  1. Isotope Production: Sourcing raw isotopes from nuclear reactors or cyclotrons.

  2. Ligand Discovery: R&D into small molecules or antibodies that bind to GCPII.

  3. Radiolabeling/Manufacturing: Combining the isotope with the ligand in specialized, high-shielded facilities.

  4. Logistics: Urgent cold-chain transportation to clinics.

  5. Administration & Monitoring: Patient dosing followed by imaging to verify target engagement.

10. Quick Recommendations for Stakeholders

  • For Manufacturers: Secure long-term supply agreements for Actinium-225 and Lutetium-177 to avoid production bottlenecks.

  • For Investors: Target biotech firms developing GCPII inhibitors for CNS indications, as this segment is currently undervalued compared to oncology.

  • For Healthcare Providers: Invest in training staff for Radioligand Therapy (RLT) administration, as this will become a standard of care by 2030.

  • For Diagnostic Labs: Adopt AI-based software for PSMA-PET quantification to provide more accurate staging for oncologists.

Table of Contents

Global Glutamate Carboxypeptidase 2 Sales Market Report 2018
1 Glutamate Carboxypeptidase 2 Market Overview
    1.1 Product Overview and Scope of Glutamate Carboxypeptidase 2
    1.2 Classification of Glutamate Carboxypeptidase 2 by Product Category
        1.2.1 Global Glutamate Carboxypeptidase 2 Market Size (Sales) Comparison by Type
        1.2.2 Global Glutamate Carboxypeptidase 2 Market Size (Sales) Market Share by Type (Product Category) in
        1.2.3 INO-5150
        1.2.4 E-2072
        1.2.5 Others
    1.3 Global Glutamate Carboxypeptidase 2 Market by Application/End Users
        1.3.1 Global Glutamate Carboxypeptidase 2 Sales (Volume) and Market Share Comparison by Application
        1.3.1 Prostate Cancer
        1.3.2 Neuropathic Pain
        1.3.3 Congnitive Impairment
        1.3.4 Glioblastoma Multiforme
        1.3.5 Others
    1.4 Global Glutamate Carboxypeptidase 2 Market by Region
        1.4.1 Global Glutamate Carboxypeptidase 2 Market Size (Value) Comparison by Region
        1.4.2 United States Glutamate Carboxypeptidase 2 Status and Prospect
        1.4.3 Europe Glutamate Carboxypeptidase 2 Status and Prospect
        1.4.4 China Glutamate Carboxypeptidase 2 Status and Prospect
        1.4.5 Japan Glutamate Carboxypeptidase 2 Status and Prospect
        1.4.6 Southeast Asia Glutamate Carboxypeptidase 2 Status and Prospect
        1.4.7 India Glutamate Carboxypeptidase 2 Status and Prospect
    1.5 Global Market Size (Value and Volume) of Glutamate Carboxypeptidase 2
        1.5.1 Global Glutamate Carboxypeptidase 2 Sales and Growth Rate
        1.5.2 Global Glutamate Carboxypeptidase 2 Revenue and Growth Rate

2 Global Glutamate Carboxypeptidase 2 Competition by Players/Suppliers, Type and Application
     2.1 Global Glutamate Carboxypeptidase 2 Market Competition by Players/Suppliers
        2.1.1 Global Glutamate Carboxypeptidase 2 Sales and Market Share of Key Players/Suppliers ()
        2.1.2 Global Glutamate Carboxypeptidase 2 Revenue and Share by Players/Suppliers ()
    2.2 Global Glutamate Carboxypeptidase 2 (Volume and Value) by Type
        2.2.1 Global Glutamate Carboxypeptidase 2 Sales and Market Share by Type ()
        2.2.2 Global Glutamate Carboxypeptidase 2 Revenue and Market Share by Type ()
    2.3 Global Glutamate Carboxypeptidase 2 (Volume and Value) by Region
        2.3.1 Global Glutamate Carboxypeptidase 2 Sales and Market Share by Region ()
        2.3.2 Global Glutamate Carboxypeptidase 2 Revenue and Market Share by Region ()
    2.4 Global Glutamate Carboxypeptidase 2 (Volume) by Application

3 United States Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    3.1 United States Glutamate Carboxypeptidase 2 Sales and Value ()
        3.1.1 United States Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        3.1.2 United States Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        3.1.3 United States Glutamate Carboxypeptidase 2 Sales Price Trend ()
    3.2 United States Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    3.3 United States Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    3.4 United States Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

4 Europe Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    4.1 Europe Glutamate Carboxypeptidase 2 Sales and Value ()
        4.1.1 Europe Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        4.1.2 Europe Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        4.1.3 Europe Glutamate Carboxypeptidase 2 Sales Price Trend ()
    4.2 Europe Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    4.3 Europe Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    4.4 Europe Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

5 China Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    5.1 China Glutamate Carboxypeptidase 2 Sales and Value ()
        5.1.1 China Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        5.1.2 China Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        5.1.3 China Glutamate Carboxypeptidase 2 Sales Price Trend ()
    5.2 China Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    5.3 China Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    5.4 China Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

6 Japan Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    6.1 Japan Glutamate Carboxypeptidase 2 Sales and Value ()
        6.1.1 Japan Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        6.1.2 Japan Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        6.1.3 Japan Glutamate Carboxypeptidase 2 Sales Price Trend ()
    6.2 Japan Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    6.3 Japan Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    6.4 Japan Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

7 Southeast Asia Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    7.1 Southeast Asia Glutamate Carboxypeptidase 2 Sales and Value ()
        7.1.1 Southeast Asia Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        7.1.2 Southeast Asia Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        7.1.3 Southeast Asia Glutamate Carboxypeptidase 2 Sales Price Trend ()
    7.2 Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    7.3 Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    7.4 Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

8 India Glutamate Carboxypeptidase 2 (Volume, Value and Sales Price)
    8.1 India Glutamate Carboxypeptidase 2 Sales and Value ()
        8.1.1 India Glutamate Carboxypeptidase 2 Sales and Growth Rate ()
        8.1.2 India Glutamate Carboxypeptidase 2 Revenue and Growth Rate ()
        8.1.3 India Glutamate Carboxypeptidase 2 Sales Price Trend ()
    8.2 India Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Players ()
    8.3 India Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Type ()
    8.4 India Glutamate Carboxypeptidase 2 Sales Volume and Market Share by Application ()

9 Global Glutamate Carboxypeptidase 2 Players/Suppliers Profiles and Sales Data
    9.1 Cerecor Inc
        9.1.1 Company Basic Information, Manufacturing Base and Competitors
        9.1.2 Glutamate Carboxypeptidase 2 Product Category, Application and Specification
            9.1.2.1 Product A
            9.1.2.2 Product B
        9.1.3 Cerecor Inc Glutamate Carboxypeptidase 2 Sales, Revenue, Price and Gross Margin ()
        9.1.4 Main Business/Business Overview
    9.2 Crescendo Biologics Ltd
        9.2.1 Company Basic Information, Manufacturing Base and Competitors
        9.2.2 Glutamate Carboxypeptidase 2 Product Category, Application and Specification
            9.2.2.1 Product A
            9.2.2.2 Product B
        9.2.3 Crescendo Biologics Ltd Glutamate Carboxypeptidase 2 Sales, Revenue, Price and Gross Margin ()
        9.2.4 Main Business/Business Overview
    9.3 Eisai Co Ltd
        9.3.1 Company Basic Information, Manufacturing Base and Competitors
        9.3.2 Glutamate Carboxypeptidase 2 Product Category, Application and Specification
            9.3.2.1 Product A
            9.3.2.2 Product B
        9.3.3 Eisai Co Ltd Glutamate Carboxypeptidase 2 Sales, Revenue, Price and Gross Margin ()
        9.3.4 Main Business/Business Overview
    9.4 Inovio Pharmaceuticals Inc
        9.4.1 Company Basic Information, Manufacturing Base and Competitors
        9.4.2 Glutamate Carboxypeptidase 2 Product Category, Application and Specification
            9.4.2.1 Product A
            9.4.2.2 Product B
        9.4.3 Inovio Pharmaceuticals Inc Glutamate Carboxypeptidase 2 Sales, Revenue, Price and Gross Margin ()
        9.4.4 Main Business/Business Overview
    ...

10 Glutamate Carboxypeptidase 2 Maufacturing Cost Analysis
    10.1 Glutamate Carboxypeptidase 2 Key Raw Materials Analysis
        10.1.1 Key Raw Materials
        10.1.2 Price Trend of Key Raw Materials
        10.1.3 Key Suppliers of Raw Materials
        10.1.4 Market Concentration Rate of Raw Materials
    10.2 Proportion of Manufacturing Cost Structure
        10.2.1 Raw Materials
        10.2.2 Labor Cost
        10.2.3 Manufacturing Process Analysis of Glutamate Carboxypeptidase 2
    10.3 Manufacturing Process Analysis of Glutamate Carboxypeptidase 2

11 Industrial Chain, Sourcing Strategy and Downstream Buyers
    11.1 Glutamate Carboxypeptidase 2 Industrial Chain Analysis
    11.2 Upstream Raw Materials Sourcing
    11.3 Raw Materials Sources of Glutamate Carboxypeptidase 2 Major Manufacturers in
    11.4 Downstream Buyers

12 Marketing Strategy Analysis, Distributors/Traders
    12.1 Marketing Channel
        12.1.1 Direct Marketing
        12.1.2 Indirect Marketing
        12.1.3 Marketing Channel Development Trend
    12.2 Market Positioning
        12.2.1 Pricing Strategy
        12.2.2 Brand Strategy
        12.2.3 Target Client
    12.3 Distributors/Traders List

13 Market Effect Factors Analysis
    13.1 Technology Progress/Risk
        13.1.1 Substitutes Threat
        13.1.2 Technology Progress in Related Industry
    13.2 Consumer Needs/Customer Preference Change
    13.3 Economic/Political Environmental Change

14 Global Glutamate Carboxypeptidase 2 Market Forecast (2018-2025)
    14.1 Global Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Price Forecast (2018-2025)
       14.1.1 Global Glutamate Carboxypeptidase 2 Sales Volume and Growth Rate Forecast (2018-2025)
       14.1.2 Global Glutamate Carboxypeptidase 2 Revenue and Growth Rate Forecast (2018-2025)
       14.1.3 Global Glutamate Carboxypeptidase 2 Price and Trend Forecast (2018-2025)
    14.2 Global Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast by Region (2018-2025)
       14.2.1 Global Glutamate Carboxypeptidase 2 Sales Volume and Growth Rate Forecast by Regions (2018-2025)
       14.2.2 Global Glutamate Carboxypeptidase 2 Revenue and Growth Rate Forecast by Regions (2018-2025)
       14.2.3 United States Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
       14.2.4 Europe Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
       14.2.5 China Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
       14.2.6 Japan Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
       14.2.7 Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
       14.2.8 India Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Growth Rate Forecast (2018-2025)
    14.3 Global Glutamate Carboxypeptidase 2 Sales Volume, Revenue and Price Forecast by Type (2018-2025)
       14.3.1 Global Glutamate Carboxypeptidase 2 Sales Forecast by Type (2018-2025)
       14.3.2 Global Glutamate Carboxypeptidase 2 Revenue Forecast by Type (2018-2025)
       14.3.3 Global Glutamate Carboxypeptidase 2 Price Forecast by Type (2018-2025)
    14.4 Global Glutamate Carboxypeptidase 2 Sales Volume Forecast by Application (2018-2025)

15 Research Findings and Conclusion

16 Appendix
    16.1 Methodology/Research Approach
        16.1.1 Research Programs/Design
        16.1.2 Market Size Estimation
        16.1.3 Market Breakdown and Data Triangulation
    16.2 Data Source
        16.2.1 Secondary Sources
        16.2.2 Primary Sources
    16.3 Disclaimer
List of Tables and Figures

    Figure Product Picture of Glutamate Carboxypeptidase 2
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume Comparison (K Pcs) by Type
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type (Product Category) in
    Figure INO-5150 Product Picture
    Figure E-2072 Product Picture
    Figure Others Product Picture
    Figure Global Glutamate Carboxypeptidase 2 Sales Comparison (K Pcs) by Application
    Figure Global Sales Market Share of Glutamate Carboxypeptidase 2 by Application in
    Figure Prostate Cancer Examples
    Table Key Downstream Customer in Prostate Cancer
    Figure Neuropathic Pain Examples
    Table Key Downstream Customer in Neuropathic Pain
    Figure Congnitive Impairment Examples
    Table Key Downstream Customer in Congnitive Impairment
    Figure Glioblastoma Multiforme Examples
    Table Key Downstream Customer in Glioblastoma Multiforme
    Figure Others Examples
    Table Key Downstream Customer in Others
    Figure Global Glutamate Carboxypeptidase 2 Market Size (Million USD) by Regions
    Figure United States Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure Europe Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure China Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure Japan Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure India Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate
    Figure Global Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate
    Figure Global Market Major Players Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) ()
    Table Global Glutamate Carboxypeptidase 2 Sales (K Pcs) of Key Players/Suppliers ()
    Table Global Glutamate Carboxypeptidase 2 Sales Share by Players/Suppliers ()
    Figure  Glutamate Carboxypeptidase 2 Sales Share by Players/Suppliers
    Figure  Glutamate Carboxypeptidase 2 Sales Share by Players/Suppliers
    Figure Global Glutamate Carboxypeptidase 2 Revenue (Million USD) by Players/Suppliers ()
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) by Players/Suppliers ()
    Table Global Glutamate Carboxypeptidase 2 Revenue Share by Players/Suppliers ()
    Table  Global Glutamate Carboxypeptidase 2 Revenue Share by Players
    Table  Global Glutamate Carboxypeptidase 2 Revenue Share by Players
    Table Global Glutamate Carboxypeptidase 2 Sales (K Pcs) and Market Share by Type ()
    Table Global Glutamate Carboxypeptidase 2 Sales Share (K Pcs) by Type ()
    Figure Sales Market Share of Glutamate Carboxypeptidase 2 by Type ()
    Figure Global Glutamate Carboxypeptidase 2 Sales Growth Rate by Type ()
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) and Market Share by Type ()
    Table Global Glutamate Carboxypeptidase 2 Revenue Share by Type ()
    Figure Revenue Market Share of Glutamate Carboxypeptidase 2 by Type ()
    Figure Global Glutamate Carboxypeptidase 2 Revenue Growth Rate by Type ()
    Table Global Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Market Share by Region ()
    Table Global Glutamate Carboxypeptidase 2 Sales Share by Region ()
    Figure Sales Market Share of Glutamate Carboxypeptidase 2 by Region ()
    Figure Global Glutamate Carboxypeptidase 2 Sales Growth Rate by Region in
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) and Market Share by Region ()
    Table Global Glutamate Carboxypeptidase 2 Revenue Share (%) by Region ()
    Figure Revenue Market Share of Glutamate Carboxypeptidase 2 by Region ()
    Figure Global Glutamate Carboxypeptidase 2 Revenue Growth Rate by Region in
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) and Market Share by Region ()
    Table Global Glutamate Carboxypeptidase 2 Revenue Share (%) by Region ()
    Figure Revenue Market Share of Glutamate Carboxypeptidase 2 by Region ()
    Figure Global Glutamate Carboxypeptidase 2 Revenue Market Share by Region in
    Table Global Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Market Share by Application ()
    Table Global Glutamate Carboxypeptidase 2 Sales Share (%) by Application ()
    Figure Sales Market Share of Glutamate Carboxypeptidase 2 by Application ()
    Figure Global Glutamate Carboxypeptidase 2 Sales Market Share by Application ()
    Figure United States Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure United States Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure United States Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table United States Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table United States Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table United States Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure United States Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Figure Europe Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure Europe Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure Europe Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure Europe Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Figure China Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure China Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure China Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table China Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table China Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table China Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure China Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Figure Japan Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure Japan Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure Japan Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure Japan Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Figure India Glutamate Carboxypeptidase 2 Sales (K Pcs) and Growth Rate ()
    Figure India Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate ()
    Figure India Glutamate Carboxypeptidase 2 Sales Price (USD/Pcs) Trend ()
    Table India Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Players ()
    Table India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players ()
    Figure India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Players in
    Table India Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Type ()
    Table India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type ()
    Figure India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Type in
    Table India Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) by Application ()
    Table India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application ()
    Figure India Glutamate Carboxypeptidase 2 Sales Volume Market Share by Application in
    Table Cerecor Inc Basic Information List
    Table Cerecor Inc Glutamate Carboxypeptidase 2 Sales (K Pcs), Revenue (Million USD), Price (USD/Pcs) and Gross Margin ()
    Figure Cerecor Inc Glutamate Carboxypeptidase 2 Sales Growth Rate ()
    Figure Cerecor Inc Glutamate Carboxypeptidase 2 Sales Global Market Share ()
    Figure Cerecor Inc Glutamate Carboxypeptidase 2 Revenue Global Market Share ()
    Table Crescendo Biologics Ltd Basic Information List
    Table Crescendo Biologics Ltd Glutamate Carboxypeptidase 2 Sales (K Pcs), Revenue (Million USD), Price (USD/Pcs) and Gross Margin ()
    Figure Crescendo Biologics Ltd Glutamate Carboxypeptidase 2 Sales Growth Rate ()
    Figure Crescendo Biologics Ltd Glutamate Carboxypeptidase 2 Sales Global Market Share ()
    Figure Crescendo Biologics Ltd Glutamate Carboxypeptidase 2 Revenue Global Market Share ()
    Table Eisai Co Ltd Basic Information List
    Table Eisai Co Ltd Glutamate Carboxypeptidase 2 Sales (K Pcs), Revenue (Million USD), Price (USD/Pcs) and Gross Margin ()
    Figure Eisai Co Ltd Glutamate Carboxypeptidase 2 Sales Growth Rate ()
    Figure Eisai Co Ltd Glutamate Carboxypeptidase 2 Sales Global Market Share (
    Figure Eisai Co Ltd Glutamate Carboxypeptidase 2 Revenue Global Market Share ()
    Table Inovio Pharmaceuticals Inc Basic Information List
    Table Inovio Pharmaceuticals Inc Glutamate Carboxypeptidase 2 Sales (K Pcs), Revenue (Million USD), Price (USD/Pcs) and Gross Margin ()
    Figure Inovio Pharmaceuticals Inc Glutamate Carboxypeptidase 2 Sales Growth Rate ()
    Figure Inovio Pharmaceuticals Inc Glutamate Carboxypeptidase 2 Sales Global Market Share ()
    Figure Inovio Pharmaceuticals Inc Glutamate Carboxypeptidase 2 Revenue Global Market Share ()
    Table Production Base and Market Concentration Rate of Raw Material
    Figure Price Trend of Key Raw Materials
    Table Key Suppliers of Raw Materials
    Figure Manufacturing Cost Structure of Glutamate Carboxypeptidase 2
    Figure Manufacturing Process Analysis of Glutamate Carboxypeptidase 2
    Figure Glutamate Carboxypeptidase 2 Industrial Chain Analysis
    Table Raw Materials Sources of Glutamate Carboxypeptidase 2 Major Players in
    Table Major Buyers of Glutamate Carboxypeptidase 2
    Table Distributors/Traders List
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Price (USD/Pcs) and Trend Forecast (2018-2025)
    Table Global Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) Forecast by Regions (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume Market Share Forecast by Regions (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume Market Share Forecast by Regions in 2025
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) Forecast by Regions (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Revenue Market Share Forecast by Regions (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Revenue Market Share Forecast by Regions in 2025
    Figure United States Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure United States Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Figure Europe Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure Europe Glutamate Carboxypeptidase 2 Revenue and Growth Rate Forecast (2018-2025)
    Figure China Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure China Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Figure Japan Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure Japan Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure Southeast Asia Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Figure India Glutamate Carboxypeptidase 2 Sales Volume (K Pcs) and Growth Rate Forecast (2018-2025)
    Figure India Glutamate Carboxypeptidase 2 Revenue (Million USD) and Growth Rate Forecast (2018-2025)
    Table Global Glutamate Carboxypeptidase 2 Sales (K Pcs) Forecast by Type (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Sales Volume Market Share Forecast by Type (2018-2025)
    Table Global Glutamate Carboxypeptidase 2 Revenue (Million USD) Forecast by Type (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Revenue Market Share Forecast by Type (2018-2025)
    Table Global Glutamate Carboxypeptidase 2 Price (USD/Pcs) Forecast by Type (2018-2025)
    Table Global Glutamate Carboxypeptidase 2 Sales (K Pcs) Forecast by Application (2018-2025)
    Figure Global Glutamate Carboxypeptidase 2 Sales Market Share Forecast by Application (2018-2025)
    Table Research Programs/Design for This Report
    Figure Bottom-up and Top-down Approaches for This Report
    Figure Data Triangulation
    Table Key Data Information from Secondary Sources
    Table Key Data Information from Primary Sources

Key Players

Beyond the initial list of biotech firms, the market is now dominated by major pharmaceutical giants and radiopharmaceutical specialists:

  • Novartis AG (Switzerland) – Leader in PSMA-targeted radioligand therapy.

  • Lantheus Holdings, Inc. (USA) – Specialized in PSMA-PET imaging agents.

  • Telix Pharmaceuticals (Australia) – Focused on molecularly targeted radiation.

  • Bayer AG (Germany) – Developing alpha-emitting GCPII conjugates.

  • Eli Lilly (Point Biopharma) (USA) – Expanding into next-gen radioligands.

  • Amgen Inc. (USA) – Researching BiTE (Bispecific T-cell Engager) molecules targeting GCPII.

  • Curium (France) – Global leader in diagnostic isotope manufacturing.

  • Blue Earth Diagnostics (UK) – Specialized in molecular imaging for prostate cancer.

  • Avalo Therapeutics (formerly Cerecor) (USA).

  • Inovio Pharmaceuticals (USA).

3. Comprehensive Market Segmentation

By Product/Molecule Type

  • Radioligand Therapies: High-growth segment (e.g., Lu-177 labeled molecules).

  • Monoclonal Antibodies: Used for both delivery of toxins and immune activation.

  • Small Molecule Inhibitors: Primarily focused on neurological applications and PET imaging.

  • Bispecific Antibodies: Engineering immune cells to target GCPII-expressing tumors.

By Application

  • Oncology (Prostate Cancer): The largest segment, covering biochemical recurrence imaging and therapy for mCRPC (metastatic castration-resistant prostate cancer).

  • Neurology (CNS Disorders): Researching GCPII inhibition to treat neuropathic pain, Schizophrenia, and ALS by regulating synaptic glutamate.

  • Other Cancers: Emerging research into GCPII expression in the neovasculature of solid tumors (e.g., kidney and bladder cancers).

By End-User

  • Specialty Hospitals & Oncology Centers: Primary hubs for therapeutic administration.

  • Diagnostic Imaging Centers: Utilizing PSMA-PET scans for early detection.

  • Academic & Research Institutes: Driving the pipeline for CNS-related applications.

4. Regional Analysis

  • North America: Occupies the largest revenue share (approx. 45%). The rapid adoption of PSMA-PET imaging and FDA approvals for radioligand therapies drive this market.

  • Europe: A stronghold for radiopharmaceutical innovation, particularly in Germany and Switzerland, where early-access programs for targeted alpha therapy are prominent.

  • Asia-Pacific: The fastest-growing region. Increasing healthcare expenditure in China and India, combined with a rising incidence of prostate cancer, is driving localized manufacturing of GCPII-targeted agents.

  • LAMEA: Emerging infrastructure for nuclear medicine in Brazil and the GCC countries is creating new market entry points.

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